Persian velar glide [w], unlike the palatal glide [j], does not serve a contrastive EXTRA-HOLD SHAPING SPRAY function in Persian phonology since it has incomplete distribution, occurring only in few words after the mid back vowel /o/.Thus, [w] is described as an allophone of the phoneme /v/.Furthermore, it has been assumed that [w] in [ow] may be d
Efficacy and Safety of PD-1 Inhibitors Monotherapy for Elderly Patients with Advanced Non-small Cell Lung Cancer
Background Immunotherapy represented by programmed death protein-1 (PD-1) inhibitors has gradually become the standard treatment of advanced non-small cell lung cancer (NSCLC) in recent years, changing the treatment landscape of advanced NSCLC.However, most PD-1-related studies excluded patients with NSCLC more than 70 or 75 years, resulting in rel
Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris
Abstract Background Pichia pastoris is widely used CLIPPER OIL as a production platform for heterologous proteins and model organism for organelle proliferation.Without a published genome sequence available, strain and process development relied mainly on analogies to other, well studied yeasts like Saccharomyces cerevisiae.Results To investigate s